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Small Fiber Neuropathy Market Insights, Treatment and Market Growth by DelveInsight

DelveInsight has launched a new report on Small Fiber Neuropathy Market

Small Fiber Neuropathy (SFN) is a condition that generally affects the nervous system and is marked by severe pain attacks. It occurs when damage to the peripheral nerves predominantly or entirely affects the small myelinated (Aδ) fibers or unmyelinated C fibers thus called as Small Fiber Peripheral Neuropathy. It generally affects the small nerve fibers present in the skin and those responsible to mediate pain and thermal sensation. The specific fiber types involved in this process include both small somatic and autonomic fibers.

Small Fiber Neuropathy Market detailed historical & forecasted market covering the United States, EU5, and Japan from 2017–2030

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Small Fiber Neuropathy Market Overview

SFN is caused by mutations in the SCN9A or SCN10A gene. Both the gene instructs the production of the alpha subunit for the NaV1.7 sodium channel. The SCN9A gene mutations result in NaV1.7 sodium channels that do not close completely when the channel is turned off and many SCN10A gene mutations results in opening of NaV1.8 sodium channels that more easily than usual. This increase in sodium ions enhances transmission of pain signals, causing individuals to be more sensitive to stimulation.

SFN is mainly associated with autoimmune diseases, sodium channel gene variants, diabetes mellitus, and vitamin B12 deficiencies, although in more than one-half of patients no etiology can be identified. Based on these etiologies, it can be divided in to four sub-groups such as Acquired SFN, Hereditary SFN, Syndromic SFN, and Idiopathic SFN.

The symptoms of SFN include bowel problems, urinary issues, rapid heartbeat, abnormal sweating, and dry eyes and mouth. It is generally characterized by severe pain attacks that begin in the feet or hands.

Small Fiber Neuropathy Key Strengths

  • 11 Year Forecast
  • 7MM Coverage
  • Epidemiology Segmentation
  • Drugs Uptake
  • Highly Analyzed Market
  • Key Cross Competition
  • Small Fiber Neuropathy Market Size by Country
  • Small Fiber Neuropathy Market Size by Therapy

Small Fiber Neuropathy Treatment

There is no cure for SFN. The frequency of SFN is not clearly known and it can vary according to ethnicity and gender. The progressiveness of this disease and its complications cause debilitating effects on the health of patients and impose a significant burden, both economically and on the quality of life. Thus, a lot of research has been done in this space to find the ways to manage the disease. Pain management and other symptomatic therapies are main components of the treatment system for patients with neuropathy. Non-pharmacological therapies such as transcutaneous electrical nerve stimulation, acupuncture, physical therapy and massage, and others are also used.

Small Fiber Neuropathy Market Insights

Head-to-head trials of medications and long-term outcome data for small fiber neuropathies are lacking. When possible, disease-specific treatment guidelines should be selected for management of pain in small fiber neuropathy (e.g., diabetes, HIV, or chemotherapy). At present, therapeutic strategies are largely symptomatic. Three main categories of drugs are most commonly used for treating neuropathic pain: antidepressants, anti-epileptics, and opioids.

Key companies of the report

  • Vertex Pharmaceuticals
  • Biogen

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Table of content

  1. Key Insights
  2. Executive Summary of Small Fiber Neuropathy (SFN)
  3. Competitive Intelligence Analysis for Small Fiber Neuropathy (SFN)
  4. Small Fiber Neuropathy (SFN) : Market Overview at a Glance
  5. Small Fiber Neuropathy (SFN) : Disease Background and Overview
  6. Patient Journey
  7. Small Fiber Neuropathy (SFN) Epidemiology and Patient Population
  8. Treatment Algorithm, Current Treatment, and Medical Practices
  9. Unmet Needs
  10. Key Endpoints of Small Fiber Neuropathy (SFN) Treatment
  11. Marketed Products
  12. Emerging Therapies
  13. Small Fiber Neuropathy (SFN) : Seven Major Market Analysis
  14. Attribute analysis
  15. 7MM: Market Outlook
  16. Access and Reimbursement Overview of Small Fiber Neuropathy (SFN)
  17. KOL Views
  18. Market Drivers
  19. Market Barriers
  20. Appendix
  21. DelveInsight Capabilities
  22. Disclaimer
  23. About DelveInsight

 Reasons to buy this report

  • The report will help in developing business strategies by understanding trends shaping and driving the Small Fiber Neuropathy (SFN) market
  • To understand the future market competition in the Small Fiber Neuropathy (SFN) market and Insightful review of the key market drivers and barriers
  • Organize sales and marketing efforts by identifying the best opportunities for Small Fiber Neuropathy (SFN) in the US, Europe (Germany, Spain, Italy, France, and the United Kingdom) and Japan
  • Identification of strong upcoming players in the market will help in devising strategies that will help in getting ahead of competitors
  • Organize sales and marketing efforts by identifying the best opportunities for Small Fiber Neuropathy (SFN) market
  • To understand the future market competition in the Small Fiber Neuropathy (SFN) market

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